Characterise the natural history of patients with alpha-1 antitrypsin deficiency in routine care patients with/without COPD

This study aims to determine trends in AATD prevalence, incidence and mortality in the UK population using large databases from primary care records, in all and by subgroups of major determinants (gender, age, calendar year, geography, smoking status, with/without COPD, other comorbidities, …), and to characterize the UK AATD population natural history versus a reference population with/without COPD.

The primary objective of the study will be to establish the extent of the AATD burden in the UK, and to benchmark it with other respiratory and non-respiratory conditions.

Lead Investigator:
Dr Joan B Soriano
Research Team:
Dr Ravi Mahadeva
Dr Rupert Jones
Dr Marc Miravitlles

Status: Active Study
Documents and Publications:
Final Publications
Additional Material

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