Comparative effectiveness of Step three treatment options in children with asthma

The primary focus is to investigate the relationship between a step-up in asthma treatment (i.e. addition of a long-acting β-agonist (LABA), leukotriene receptor antagonist (LTRA) or increased ICS dose) in children aged 5-12 and the impact on asthma control over a 12 month period.

As a secondary objective, the study will also investigate the relationship between change in inhaler type on the same therapy dose (e.g. DPI to MDI, DPI to MDI) and the impact on asthma control over a 12 month period.

Lead Investigators:
Professor David Price, Steve Turner
Research Team:
Catherine Hutton, Lianne Mabin, Annie Burden, Vicky Thomas, Muzammil Ali, Francesca Barion, Julie von Ziegenweidt, Daniel West, Anna Rigazio, Shuna Gould
Status: Completed Study
Support: Respiratory Effectiveness Group
Registration: ENCEPP/SDPP/10483
Documents and Publications:
Protocol
Abstracts
Presentations
Final Publications
Additional Material