Implications of ICS particle size on the management of respiratory patients with comorbid GERD

Hypothesis

  • The mechanisms by which high BMI and GERD impair asthma control could involve increased distal airway inflammation
  • Differential effect of EF and standard-size ICS may help exploring this involvement of small airways.

Objectives

  • Evaluate the comparative effectiveness of EF and NEF ICS in asthma patients ± GERD ± overweight/obesity
  • Determine the relationship between overweight/obesity and GERD as determinants of poor asthma control

Lead Investigator:
Nicolas Roche
Research Team:
Status: Proposed Study, Seeking Funding
Support: 
Registration:
Documents and Publications:
Protocol
Abstracts
Presentations
Final Publications