Implications of steroid tailoring on treatment outcomes in patients with COPD managed in routine care

The aim of the study is to evaluate the effect of ICS withdrawal (evaluated as dose reduction and cessation) on real-world clinical outcomes in patients with confirmed COPD who are adherent to ICS therapy (medication possession ratio [MPR] ≥70%).
Lead Investigator:
Dirkje S. Postma: University Medical Center Groningen, Groningen, The Netherlands
Research Team:
Working Group Lead – Marc Miravitlles: Pneumology Department, Vall d’ Hebron University Hospital, Barcelona, Spain
David Price: Professor of Primary Care Respiratory Medicine, University of Aberdeen, Aberdeen, UK; Owner of Optimum Patient Care Ltd
Helgo Magnussen: Pulmonary Research Institute at Lung Clinic Grosshansdorf, Germany
Dermot Ryan: Honorary Fellow at the University of Edinburgh; Consultant at Optimum Patient Care Ltd, Cambridge, UK
Ronald Dandurand: Montreal Chest Institute & Meakins-Christie Laboratories, McGill University Health Centre, Montreal, QC, Canada
Jens Dollerup: Dollerup Medical Consultancy, Copenhagen, Denmark
Alberto Papi: S. Anna University Hospital, Ferrara, Italy
Nicolas Roche: University of Paris Descartes, Paris, France
Jennifer Quint: Imperial College, London, UK
Therese Lapperre: Singapore General Hospital, Singapore, Singapore
Caroline Gouder: Mater Dei Hospital, Valletta, Malta
Richard Costello: Royal College of Surgeons, Dublin, Ireland
Juan José Soler-Cataluña: Pneumology Department, Hospital Arnau de Vilanova, Valencia, Spain and CIBER de Enfermedades Respiratorias (CIBERES)
Faisal Yunus: Department of Pulmonology and Respiratory Medicine, Universitas Indonesia (FMUI), Jakarta, Indonesia
Bernardino Alcazar Navarrete: Respiratory Department, Hospital de Alta Resolucion, Granada, Spain
David Halpin: Department of Respiratory Medicine, Royal Devon & Exeter Hospital, Exeter
Akio Niimi: Department of Respiratory Medicine, Kyoto University Graduate School of Medicine
Alison Chisholm: Chief Scientific Officer of the Respiratory Effectiveness Group, Cambridge, UK
Status: Proposed Study, Seeking Funding
Support:
Registration:
Documents and Publications
Protocol
Abstracts
Presentations
Final Publications
Additional Material