Real-life asthma endpoint validation

Lead Investigator:

Richard Martin, National Jewish Health, Denver, Colorado, USA

Research Team:

The research team will be made up of members of the Respiratory Effectiveness Group; data analysis and statistical support are being provided by Research in Real Life (Ltd). The REG collaborators are:

  • David Price, UK
  • Gene Colice, USA
  • Todor Popov, Bulgaria
  • Janet Holbrook, USA
  • Emilio Pizzichini, Brazil
  • Nikos Papadopoulos, Greece
  • Guy Brusselle, Belgium
  • Helen Reddel, Australia
  • Alex Dima, Netherlands

Status: Active


The Respiratory Effectiveness Group



Short Description:

  • The aim of this study is to validate a series of objective asthma control measures that have been used in published real-life respiratory research.
  • The outcome measures will be compared and contrasted to patient-reported outcomes and/or gold-standard, validated asthma control tools and measures (as appropriate).
  • Where possible, their relevance, responsiveness and predictive value will also be assessed and a rank order of outcomes (and possibly hierarchical modelling) will be established to aid in appropriate outcome selection for future studies.


Documents and Publications





Final publications

Additional Material

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