Addition of Antibiotics to Usual Care Management of Asthma Exacerbations: a real-life comparative effectiveness study

Lead Investigators

  • Nikolaos G. Papadopoulos, Professor of Allergy and Pediatric Allergy, Center for Pediatrics and Child Health,Institute of Human Development, The University of Manchester, Royal Manchester Children’s Hospital, Manchester, UK
  • Clare Murray, University of Manchester and Royal Manchester Children’s Hospital, Manchester, UK

Research Team

  • David Price, Professor of Primary Care Respiratory Medicine at the University of Aberdeen, UK
  • Steve Turner, Clinical Lecturer, University of Aberdeen, UK
  • Wim van Aalderen, Emma Children’s Hospital AMC, Amsterdam, The Netherlands
  • Wanda Phipatanakul, Boston Children’s Hospital, Boston, MA, USA
  • Theresa Gulibert, Children’s Hospital Medical Center, Cincinnati, USA
  • Stan Szefler, Children’s Hospital Colorado, Denver, Co, USA
  • Alan Kaplan, Primary Care Physician, Toronto, Canada
  • James Paton, Clinical Reader (Child Health), University of Glasgow

Status: Active


The Respiratory Effectiveness Group

Registration: width=”2/3″]Short Description

The aim of the proposed study is to evaluate the comparative effectiveness of managing asthma exacerbations with oral steroids alone (i.e. usual care) versus combination antibiotics and oral steroids in paediatric and adult asthma populations. Secondary objectives of the study will be to explore the differential usage and associated outcomes of different classes of antibiotics, as used in this context.Documents and Publications

  • Protocol
  • Abstracts
  • Presentations
  • Final Publications
  • Additional Material