Predictors of asthma risk

Title: Predictors of asthma risk ­– patient characteristics associated with the “frequent exacerbator phenotype”

Lead Investigator: Mike Thomas, University of Southampton

Research Team: TBC shortly

Short description:

  • Hypothesis: there is a frequent-exacerbation phenotype in asthma that results in increased risk of asthma exacerbations. It may be possible to identify patients with this phenotype using routine data collected in primary care.
  • Aims:
    • To undertake a descriptive analysis of longitudinal patient data. Prescribed oral steroid courses will be mapped for all asthma patients over a 5-year period.
    • Investigate individual patient characteristics associated with high and low frequency of asthma exacerbations
    • Carry out multivariate modelling to weight individual characteristics and identify a possible composite group of characteristics strongly associated with frequent asthma exacerbations (that could be used to inform a clinical decision support tool)

Status: Due to commence, Spring 2013

Links (these links will become activated as the various study outputs become available):

  • Abstracts
  • Posters
  • Presentations
  • Final publications

Contact us at if you are interested in collaborating on this study, or would like to find out further information about the protocol.

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