Clinical implications of combining antibiotics with usual care (oral steroids) for the management of asthma exacerbations

The aim of the proposed study is to evaluate the comparative effectiveness of managing asthma exacerbations with oral steroids alone (i.e. usual care) versus combination antibiotics and oral steroids in paediatric and adult asthma populations. Secondary objectives of the study will be to explore the differential usage and associated outcomes of different classes of antibiotics, as used in this context.
Lead Investigator:
Lead Investigators
• Nikolaos G. Papadopoulos, Professor of Allergy and Pediatric Allergy, Center for Pediatrics and Child Health,Institute of Human Development, The University of Manchester, Royal Manchester Children’s Hospital, Manchester, UK
• Clare Murray, University of Manchester and Royal Manchester Children’s Hospital, Manchester, UK
Research Team:
• David Price, Professor of Primary Care Respiratory Medicine at the University of Aberdeen, UK
• Steve Turner, Clinical Lecturer, University of Aberdeen, UK
• Wim van Aalderen, Emma Children’s Hospital AMC, Amsterdam, The Netherlands
• Wanda Phipatanakul, Boston Children’s Hospital, Boston, MA, USA
• Theresa Gulibert, Children’s Hospital Medical Center, Cincinnati, USA
• Stan Szefler, Children’s Hospital Colorado, Denver, Co, USA
• Alan Kaplan, Primary Care Physician, Toronto, Canada
• James Paton, Clinical Reader (Child Health), University of Glasgow
Status: Active Study
Support:
Registration: ENCePP: ENCEPP/SDPP/12132
Documents and Publications
Protocol 
Abstracts
Presentations
Final Publications
Additional Material