This study intends to explore:
- To what extent and in what context adherence may be considered an asthma outcome, or/and a predictor of asthma outcomes by conducting an observational study designed to investigate the bi-directional relationship between database markers of asthma treatment adherence and asthma control (i.e. What is the impact of adherence, and change in adherence, on asthma outcomes, and vice versa?).
- Clinically meaningful adherence and outcomes thresholds will be explored by treating them as continuous variables and estimating linear/nonlinear relationships and meaningful cut-off points.
Miguel Román Rodríguez
Eric van Ganse