Validation of multi-dimensional indices (ADO, DOSE) and GOLD categorisation in routine care patients with COPD

Global Obstructive Lung Disease (GOLD) categories for chronic obstructive pulmonary disease (COPD) are recommended for severity assessment in clinical care. There is a need to understand their value in routine clinical settings and compare them with other multidimensional assessment measures.

An observational cohort study using databases comprising 5486 primary care COPD patients from UK Sweden, and Holland.

The GOLD categories, DOSE and ADO indices, associations with (i) current health status measured by the CCQ and SGRQ; exacerbations and hospital admissions and (ii) future exacerbations, admissions and mortality. The distribution into GOLD categories and future risk associated with the categories.

Lead Investigator:
Dr Rupert Jones
Research Team:
David Price, Niels H. Chavannes, Amanda Lee, Björn Ställberg, Karin Lisspers, Josefin Sundh and Michael Hyland.
On behalf of the UNLOCK group of the IPCRG.

Status: Active Study
Support: Respiratory Effectiveness Group, UNLOCK Group of the IPCRG
Registration: 
Documents and Publications:
Protocol
Abstracts
Presentations
Final Publications:
Primary Care Respiratory Medicine
Additional Material