Utilise routine care data to develop a risk prediction model patients with asthma

This study aims to identify patient characteristics recorded within routine primary care datasets that are associated with increased risk of frequent asthma exacerbations, with the ultimate goal of:

1. Characterising the frequent exacerbator subgroup of asthma patients
2. Identifying individual risk factors associated with increased future exacerbation risk
3. Exploring clusters of risk factors associated with increased risk of future exacerbation risk.
Lead Investigator:
Mike Thomas, Professor of Primary Care Research at the University of Southampton.
Research Team:
David Price: Primary Care Respiratory Society UK, Professor of Primary Care Respiratory Medicine, University of Aberdeen, UK; Director Optimum Patient Care Ltd and Research in Real Life Ltd
John Blakey: Liverpool School of Tropical Medicine, Aintree University Hospital, North Mersey HIS, UK
Vibeke Backer: Dept of Respiratory Medicine L, Respiratory Research Unit, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark
Lynn Josephs: Primary Care research, University of Aberdeen
Ian Pavord: Institute for Lung Health, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK
Borislav Dimitrov: Senior Lecturer in Medical Statistics at the University of Southampton
Dirkje Postma: Professor of Pulmonary Medicine at the University of Groningen and the University Medical Center of Groningen
Alberto Papi: Professor of Respiratory Medicine and Director of the Section of Respiratory Diseases of the Department of Clinical And Experimental Medicine of the University of Ferrara at S.Anna University Hospital, Ferrara
Alexandra Dima: Researcher in Health Psychology, Department of Communication Science, University of Amsterdam, The Netherlands
Todor Popov: Professor at Clinical Centre of Allergology in Sofia
Hilary Pinnock: Principal in General Practice, Whitstable Medical Practice, UK; Reader, Allergy and Respiratory Research Group, Centre for Population Health Sciences: GP Section, University of Edinburgh, UK
Iain Small: General Practitioner from Peterhead, Aberdeenshire, UK Chair of the Primary Care Respiratory Society in the UK; Trustee of Asthma UK
Alan Kaplan: Family physician, Ontario, Canada and Chair of the Respiratory Medicine Special Interest Focus Group of the College of Family Physicians of Canada
Cindy Rand: Professor of Medicine, John Hopkins University, USA
Janet Holbrook: Associate Professor of Epidemiology, Johns Hopkins Center for Clinical Trials, USA
Emilio Pizzichini: Head of the Pulmonology Department of the Universidade Federal de Santa Catarina – UFSC, Federal University of Santa Catarina – School of Medicine, Florianópolis, Brazil
Gene Colice: Chest Physician, Pulmonary, Critical Care and Respiratory Services, Washington Hospital Center, and The George Washington University School of Medicine
Samantha Walker: Executive Director, Research & Policy and Deputy Chief Executive, Asthma UK
Alison Chisholm: Respiratory Effectiveness Group Implementation Manager
Status: Active Study
Support: Respiratory Effectiveness Group
Registration: ENCEPP EUPAS4869
Documents and Publications:
Protocol
Abstracts
Presentations
Final Publications
Additional Material